Approximately 20,000 Rangers supporters are expected to attend the match itself after the team’s allocation was doubled in a late ticket boost to travelling supporters.
However, other fans will be able to watch the game across the city’s bars and clubs, as well as from a big screen at the La Cartuja stadium in the outskirts of the city.
Ahead of the match, many celebs have taken to social media to send the Gers their best wishes.
Scots comedian Janey Godley said: “As a Rangers fan, I am wishing the team well tonight ! Stay safe and enjoy Seville – my wee daddy will “up there” waving his Rangers scarf – I miss watching the match with him.”
Prime Minister Boris Johnson also tweeted a good luck video from his official Twitter account.
River City star Stephen Purdon travelled to Seville with his mate, wrestling star Grado and the pair have been living it up in the sunshine.
Stephen tweeted: “Finally in Seville with the big man @gradowrestling.”
Get the latest celebrity gossip and telly news sent straight to your inbox. Sign up to our weekly Showbiz newsletterhere.